BIODEGRADATION OF FOUR CALCIUM-PHOSPHATE CERAMICS - INVIVO RATES AND TISSUE INTERACTIONS

被引:59
作者
RAMSELAAR, MMA
DRIESSENS, FCM
KALK, W
DEWIJN, JR
VANMULLEM, PJ
机构
[1] Department of Oral Function and Prosthetic Dentistry, Dental School, University of Nijmegen
[2] Department of Biomaterials, State University of Leiden
[3] Department of Oral Histology, University of Nijmegen
关键词
D O I
10.1007/BF00703460
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
To prevent exposure of artificial tooth root implants, a resorbable root implant may be developed, that in time will resorb in a vertical direction at the same rate as the alveolar ridge does after the loss of the natural teeth. Implants of four calcium phosphates: rhenanite, beta-tricalcium phosphate, hydroxylapatite and magnesium-whitlockite were measured during in vivo resorption and their interactions with the surrounding tissues at experimental periods of 6 weeks and 3 months were investigated. It was shown that a sequence of progressive resorption in vitro does not correlate with the resorption rates found in this in vivo experiment. In vivo hydroxylapatite was found to be less resorbable than magnesium-whitlockite and rhenanite less resorbable than beta-tricalcium phosphate. Tissue interactions showed that resorption of the calcium phosphates was positively related to the number of osteoclast-like cells and did not completely correlate with the resorption measurements insofar that most rhenanite implants showed a more reactive peri-implant with the largest number of osteoclast-like cells, strongly affecting the implant surface. In contrast, two rhenanite implants showed intimate contact with bone after initial resorption. Because of this divergent reaction with rhenanite, further in vivo investigation on this material is proposed.
引用
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页码:63 / 70
页数:8
相关论文
共 20 条
[1]  
Denissen H.W., De Groot K., J. Prosthet. Dent., 42, (1979)
[2]  
Veldhuis H., Driessen T., Denissen H.W., De Groot K., Clin. Prev. Dent., 6, (1984)
[3]  
Quinn J.W., Kent J.N., Hunter R.G., Schaffer C.M., JADA, 110, (1985)
[4]  
Kangvonkit P., Matukas V.J., Castleberry D.J., Int. J. Oral Maxillofac. Surg., 15, (1986)
[5]  
Bell D.H., J. Prosth. Dent., 56, (1986)
[6]  
Kwon H.J., El Deeb M., Morstad, Waite D., J. Oral Maxillofac Surg., 44, (1986)
[7]  
Cranin A.N., Ronen E., Shpuntoff R., Tobin G., Dibling J.B., J. Biomed. Mater. Res., 22, (1988)
[8]  
Brook I.M., Sattayasanskul W., Lamb D.J., Br. Dent. J., 164, (1988)
[9]  
Raelaar M.M.A., Van Mullem P.J., De Wijn J.R., J. Dent., 14, (1986)
[10]  
Terpstra R.A., Driessens F.C.M., Schaeken H.G., Z. Anorg. Allg. Chem., 507, (1983)