CROSSOVER TRIALS COMPARING SEVERAL TREATMENTS

被引：23

作者：

NEWCOMBE, RG

机构：

[1] Department of Medical Computing and Statistics, University of Wales College of Medicine, Cardiff

来源：

JOURNAL OF CLINICAL PERIODONTOLOGY | 1992年 / 19卷 / 10期

关键词：

CROSSOVER STUDIES; LATIN SQUARES; BALANCED CARRYOVER; ORAL HYGIENE;

D O I：

10.1111/j.1600-051X.1992.tb02171.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Designs exist for crossover studies in which the possibility of distortion by carryover effects is minimised. A novel design including 5 treatments and 15 subjects with this property is presented, along with existing designs. These designs incorporating balance for carryover effects should be used in preference to cyclical permutation designs. Statistical analysis of the resulting data is readily performed.

引用

页码：785 / 787

页数：3

共 7 条

[1] THE EFFECT OF TRICLOSAN, STANNOUS FLUORIDE AND CHLORHEXIDINE PRODUCTS ON .1. PLAQUE REGROWTH OVER A 4-DAY PERIOD [J].