MARCHESANIS SYNDROME AND CHAMBER ANGLE ANOMALIES

A child of consanguineous parents, who evidenced a fully developed syndrome of Marchesani, and most of his immediate family, who exhibited only certain features of this syndrome, were found to have chamber angle anomalies characteristic of a systemic mesodermal dysgenesis. These anomalies are also characteristic of Marfan's syndrome, a counterpart of Marchesani's syndrome, and consist of bridging pectinate strands, numerous iris processes, fraying of the iris root and anomalous angle vessels. We believe that these chamber angle changes and the systemic disorders of Marchesani's syndrome are manifestations of the same inherited disorder. © 1968.