PHARMACOKINETIC ASPECTS OF THERAPY WITH AMPICILLIN AND KANAMYCIN IN NEWBORN-INFANTS

被引：18

作者：

DRIESSEN, OMJ

SORGEDRAGER, N

MICHEL, MF

KERREBIJN, KF

HERMANS, J

机构：

[1] UNIV LEIDEN,DEPT MED STAT,NL-2333 AL LEIDEN,NETHERLANDS

[2] ERASMUS UNIV,DEPT PEDIAT,ROTTERDAM,NETHERLANDS

[3] ERASMUS UNIV,DEPT MED MICROBIOL,ROTTERDAM,NETHERLANDS

来源：

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1978年 / 13卷 / 06期

关键词：

ampicillin; kanamycin; Neonates; pharmacokinetic parameters; post-menstrual age; postnatal age;

D O I：

10.1007/BF00566325

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Standard dose-blood level relationships and pharmacokinetic parameters were determined for ampicillin in 34 neonates and for kanamycin in 27 neonates. The parameters were correlated with the postmenstrual age, the postnatal age of the newborns and with the plasma creatinine clearance. © 1978 Springer-Verlag.

引用

页码：449 / 457

页数：9

共 21 条

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[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (05) : 715 - &
[7] DRIESSEN O, UNPUBLISHED
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[9] GLADTKE E, 1973, PHARMAKOKINETIK
[10] HERMANS J, 1975, ARZNEIMITTEL-FORSCH, V25, P947

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