PULMONARY-HYPERTENSION IN CONNECTIVE-TISSUE DISEASE - CLINICAL ANALYSIS OF 60 PATIENTS IN MULTIINSTITUTIONAL STUDY

被引：42

作者：

KASUKAWA, R

NISHIMAKI, T

TAKAGI, T

MIYAWAKI, S

YOKOHARI, R

TSUNEMATSU, T

机构：

[1] Second Department of Internal Medicine, Fukushima Medical College, Fukushima, 960-12, 1, Hikarigaoka

[2] Third Department of Internal Medicine, Okayama University Medical School

[3] Department of Internal Medicine, National Medical Center

[4] Third Division of Internal Medicine, Shimane Medical University

来源：

CLINICAL RHEUMATOLOGY | 1990年 / 9卷 / 01期

关键词：

Anti-nRNP Antibody; MCTD; Prognosis; PSS; Pulmonary Hypertension; SLE;

D O I：

10.1007/BF02030243

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clinical features and prognosis of sixty patients with connective tissue disease accompanied by pulmonary hypertension (PH) (26 MCTD, 20 SLE, and 14 PSS) reported retrospectively by multiinstitutions were compared. Though the obtained data were incomplete and lacking in uniformity, no significant difference in the clinical features among the three diseases were observed except high incidence of pulmonary fibrosis and low% VC in PSS with PH patients. Statistically significant difference, however, was observed between live and dead patients of three diseases gathered in post sternal pain, pulmonary diastolic murmur, right ventricular hypertrophy on ECG and mean pressure of pulmonary artery. Higher incidence of anti-nRNP antibody was observed in SLE with PH and PSS with PH patients than with the general population. A quicker occurrence of PH and shorter survival time were observed in MCTD patients with PH than in SLE and PSS patients with PH. © 1990 Springer-Verlag.

引用

页码：56 / 62

页数：7

共 18 条

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