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THE EFFECTS OF PH, IONIC-STRENGTH AND ORGANIC-PHASE ON THE BACTERIAL ADHESION TO HYDROCARBONS (BATH) TEST

被引：16
作者：
BUNT, CR
JONES, DS
TUCKER, IG
机构：
[1] School of Pharmacy, University of Otago, Dunedin
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 99卷 / 2-3期
关键词：
ADHERENCE; BATH; PH; IONIC STRENGTH; ESCHERICHIA-COLI;
D O I：
10.1016/0378-5173(93)90350-O
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The effects of pH, ionic strength of suspending buffer and choice of organic phase upon the subsequent adherence of E. coli to organic phase in the bacterial adherence to hydrocarbons (BATH) test were investigated. It was found that both pH and ionic strength altered adherence of E. coli and the organic phase employed for the BATH test influenced the classification of adherence. Generally, E. coli showed pronounced affinity for chloroform and dichloromethane, and only intermediate affinity for xylene. Lowering pH and increasing the ionic strength of the suspending buffer resulted in increased adherence.
引用
收藏
页码：93 / 98
页数：6
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