THE NITROREDUCTASE ENZYME IN WALKER CELLS THAT ACTIVATES 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE (CB-1954) TO 5-(AZIRIDIN-1-YL)-4-HYDROXYLAMINO-2-NITROBENZAMIDE IS A FORM OF NAD(P)H DEHYDROGENASE (QUINONE) (EC-1.6.99.2)

被引:150
作者
KNOX, RJ
BOLAND, MP
FRIEDLOS, F
COLES, B
SOUTHAN, C
ROBERTS, JJ
机构
[1] INST CANC RES,MOLEC PHARMACOL UNIT,DRUG DEV SECT,BLOCK F,COTSWOLD RD,SUTTON SM2 5NG,SURREY,ENGLAND
[2] MIDDLESEX HOSP,SCH MED,CANC RES CAMPAIGN,MOLEC TOXICOL RES GRP,PROTEIN SEQUENCING FACIL,LONDON W1P 6DB,ENGLAND
关键词
D O I
10.1016/0006-2952(88)90336-X
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:4671 / 4677
页数:7
相关论文
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