THE DEVELOPMENT OF LYSOSOMAL APPARATUS .2. INCORPORATION, SUB-CELLULAR DISTRIBUTION, AND INTRAPARTICULATE HYDROLYSIS OF 131 L-ALBUMIN BY LIVER OF MICE AT PERINATAL STAGES

被引：7

作者：

BERTINI, F ^{[1
]}

MAYORGA, L ^{[1
]}

GONZALEZ, M ^{[1
]}

机构：

[1] UNIV NACL CUYO, FAC CIENCIAS MED, INST HISTOL EMBRIOL, MENDOZA, ARGENTINA

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 1981年 / 109卷 / 02期

关键词：

D O I：

10.1002/jcp.1041090211

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mouse fetuses at 15th and 18th day of gestation and newborns aged 0, 5, 10 and 15 days were i.p. injected with 131I-albumin. The degree of incorporation by liver and the intraparticulate hydrolysis of 131I-albumin in 27,000g .times. 10 min particles increased after birth. By this time, changes in subcellular distribution of 131I-albumin and marker enzymes were also observed. Following an i.p. injection of India ink, numerous hepatic cells stained with carbon particles were observed at the light microscope from day 5 of life. The lysosomal apparatus apparently acquires full capacity to incorporate colloidal particles and to degrade foreign macromolecules in the 1st wk of life.

引用

页码：281 / 287

页数：7

共 11 条

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