TARDIVE-DYSKINESIA - CLINICAL-TEST OF THE SUPER-SENSITIVITY HYPOTHESIS

被引：28

作者：

BOWERS, MB

MOORE, D

TARSY, D

机构：

[1] VET ADM HOSP, DEPT NEUROL, BOSTON, MA 02130 USA

[2] BOSTON UNIV, SCH MED, BOSTON, MA 02215 USA

[3] HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA

[4] NEW ENGLAND DEACONESS HOSP, DEPT MED, DIV NEUROL, BOSTON, MA 02215 USA

来源：

PSYCHOPHARMACOLOGY | 1979年 / 61卷 / 02期

关键词：

CSF cyclic AMP; CSF homovanillic acid; Dopamine receptor supersensitivity; Tardive dyskinesia;

D O I：

10.1007/BF00426727

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Patients with tardive dyskinesia showed no significant difference in CSF HVA when compared with groups of schizophrenic or depressives. CSF cAMP in the tardive dyskinesia group was significantly lower when compared to schizophrenics but not depressives. These results do not support a dopamine-receptor supersensitivity hypothesis in permanent tardive dyskinesia. © 1979 Springer-Verlag.

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页码：137 / 141

页数：5

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