ALTERED GROWTH-HORMONE SECRETION DURING ORAL CONTRACEPTION

被引：13

作者：

KARLSSON, R

EDEN, S

VONSCHOULTZ, B

机构：

[1] GOTHENBURG UNIV,DEPT PHYSIOL,S-41124 GOTHENBURG,SWEDEN

[2] KAROLINSKA HOSP,DEPT OBSTET & GYNECOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1990年 / 30卷 / 04期

关键词：

ORAL CONTRACEPTIVES; GROWTH HORMONE; SECRETORY PATTERN;

D O I：

10.1159/000293276

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Serum profiles of growth hormone (GH) were recorded for 24 h in 9 young healthy women before and during treatment with monophasic, combined contraceptives. During treatment, there was a change in GH secretion towards a pattern of smaller peaks at a higher frequency. The mean peak amplitude decreased from 11.2 to 7.3 mU/l, the mean peak area from 24.1 to 14.1 mU/l, and the mean interpeak interval from 4.3 to 3.0 h. The biological impact of altered GH secretion is well-known from animal experiments. A sex-steroid-induced change in GH secretion may be relevant for certain metabolic effects of oral contraceptives.

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收藏

页码：234 / 238

页数：5

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