CELL-KINETICS OF GASTROINTESTINAL TUMORS AFTER DIFFERENT NUTRITIONAL REGIMENS - A PRELIMINARY-REPORT

被引：11

作者：

FRANCHI, F

ROSSIFANELLI, F

SEMINARA, P

CASCINO, A

BARONE, C

SCUCCHI, L

机构：

[1] UNIV SACRO CUORE,INST MED,ROME,ITALY

[2] UNIV ROME LA SAPIENZA,DEPT HUMAN BIOPATHOL,ULTRASTRUCT PATHOL SECT,I-00185 ROME,ITALY

[3] UNIV ROME LA SAPIENZA,INST CLIN MED 3,ONCOL UNIT,NUTRIT UNIT,I-00185 ROME,ITALY

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 1991年 / 13卷 / 03期

关键词：

LABELING INDEX; GASTROINTESTINAL TUMORS; TOTAL PARENTERAL NUTRITION;

D O I：

10.1097/00004836-199106000-00012

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Forty-four cases of different untreated gastrointestinal tumors were studied with regard to cell kinetic activity. As a pilot experiment, we also determined the H-3-TdR Labeling Index (LI) in 28 patients in basal conditions and after 15 days of nutritional manipulation with prevalently lipid-based or glucose-based feeding to ascertain whether selective nutritional regimens could affect tumor proliferation. Preliminary results from this study indicate that a kinetic perturbation is induced in tumor cells by nutritional manipulation. Lipid-based feeding seems to produce effects similar to those of chemical or physical anticancer agents, thus suggesting a possible supporting role of nutritional manipulation in cancer treatment strategy.

引用

页码：313 / 315

页数：3

共 27 条

[1]

BAUER KD, 1987, LAB INVEST, V57, P329

[2]

BUZBY GP, 1980, CANCER, V45, P2940, DOI 10.1002/1097-0142(19800615)45:12<2940::AID-CNCR2820451208>3.0.CO

[3]

2-P

[4] PLASMA AMINO-ACIDS IN HUMAN CANCER - THE INDIVIDUAL ROLE OF TUMOR, MALNUTRITION AND GLUCOSE-TOLERANCE [J].

CASCINO, A ;

CANGIANO, C ;

CECI, F ;

FRANCHI, F ;

MENICHETTI, ET ;

MUSCARITOLI, M ;

FANELLI, FR .

CLINICAL NUTRITION, 1988, 7 (04) :213-218

[5]

CHAUVEL P, 1988, RADIOTHER ONCOL, V547, P1

[6] CHANGES IN LABELING INDEXES OF HUMAN-TUMORS AFTER IRRADIATION [J].

COURDI, A ;

TUBIANA, M ;

CHAVAUDRA, N ;

MALAISE, EP ;

LEFUR, R .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1980, 6 (12) :1639-1644

[7] CORRELATION BETWEEN INVITRO LABELING INDEXES (LIS) AND TUMOR REGRESSION FOLLOWING RADIOTHERAPY [J].

ELEQUIN, FT ;

MUGGIA, FM ;

GHOSSEIN, NA ;

AGER, PJ ;

KRISHNASWAMY, V .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1978, 4 (3-4) :207-213

[8]

ENRIONE EB, 1985, CANCER, V56, P2612, DOI 10.1002/1097-0142(19851201)56:11<2612::AID-CNCR2820561113>3.0.CO

[9]

2-7

[10]

FRIEDMAN E, 1989, CANCER, V63, P2486, DOI 10.1002/1097-0142(19890615)63:12<2486::AID-CNCR2820631221>3.0.CO

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