1-BENZYLOXY-3-(P-TOLYLSULFONYL)PROPENE AS AN ACROLEIN BETA-ANION EQUIVALENT - SYNTHESIS OF 4-SUBSTITUTED 2-BUTENOLIDES

被引：18

作者：

CRAIG, D

ETHERIDGE, CJ

SMITH, AM

机构：

[1] Department of Chemistry, Imperial College of Science, Technology and Medicine, London

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(00)60211-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithiation of 1-benzyloxy-3-(p-tolylsulfonyl)propene 6 and reaction with aldehydes gives alcohols 7. Sequential hydrolysis-cyclization, oxidation and DBU-mediated elimination of the elements of p-TolSO2H gives 4-substituted 2-butenolides 10 in good overall yield.

引用

页码：7445 / 7446

页数：2

共 5 条

[1] METHYL 3-PHENYLSULFONYL ORTHOPROPIONATE - AN EFFICIENT REAGENT FOR THE SYNTHESIS OF GAMMA-LACTONES AND BUTENOLIDES [J].