Methyl phosphotriester oligonucleotides: Facile synthesis using N-pent-4-enoyl nucleoside phosphoramidites

被引：16

作者：

Iyer, RP

Yu, D

Ho, NH

Devlin, T

Agrawal, S

机构：

[1] Hybridan Inc., One Innovation Drive, Worcester

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 25期

关键词：

D O I：

10.1021/jo00130a008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：8132 / 8133

页数：2

共 15 条

[1]

Agrawal Sudhir, 1995, Current Opinion in Biotechnology, V6, P12, DOI 10.1016/0958-1669(95)80003-4

[2] OXALYL-CPG - A LABILE SUPPORT FOR SYNTHESIS OF SENSITIVE OLIGONUCLEOTIDE DERIVATIVES [J].

ALUL, RH ;

SINGMAN, CN ;

ZHANG, GR ;

LETSINGER, RL .

NUCLEIC ACIDS RESEARCH, 1991, 19 (07) :1527-1532

[3] A CONVENIENT PROCEDURE FOR THE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDE AFFINITY COLUMNS FOR THE ISOLATION OF MESSENGER-RNA [J].

ATKINSON, T ;

GILLAM, S ;

SMITH, M .

NUCLEIC ACIDS RESEARCH, 1988, 16 (13) :6232-6232

[4]

Beaucage S. L., 1993, PROTOCOLS OLIGONUCLE, V20, P33

[5] ADVANCES IN THE SYNTHESIS OF OLIGONUCLEOTIDES BY THE PHOSPHORAMIDITE APPROACH [J].

BEAUCAGE, SL ;

IYER, RP .

TETRAHEDRON, 1992, 48 (12) :2223-2311

[6] 2 NEW ORTHOGONAL AMINE-PROTECTING GROUPS THAT CAN BE CLEAVED UNDER MILD OR NEUTRAL CONDITIONS [J].

DEBENHAM, JS ;

MADSEN, R ;

ROBERTS, C ;

FRASERREID, B .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (11) :3302-3303

[7] 2-(TRIMETHYLSILYL)ETHYL GLYCOSIDES .9. TRANSFORMATION INTO THE CORRESPONDING 1-O-ACYL SUGARS [J].

ELLERVIK, U ;

MAGNUSSON, G .

ACTA CHEMICA SCANDINAVICA, 1993, 47 (08) :826-828

[8]

HAYAKAWA M, 1995, J ORG CHEM, V60, P925

[9]

Iyer R. P., UNPUB

[10] THE AUTOMATED SYNTHESIS OF SULFUR-CONTAINING OLIGODEOXYRIBONUCLEOTIDES USING 3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE AS A SULFUR-TRANSFER REAGENT [J].

IYER, RP ;

PHILLIPS, LR ;

EGAN, W ;

REGAN, JB ;

BEAUCAGE, SL .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (15) :4693-4699

← 1 2 →