DETECTION OF REACTIVE METABOLITES INVITRO

被引：37

作者：

GARLE, MJ ^{[1
]}

FRY, JR ^{[1
]}

机构：

[1] QUEENS MED CTR,SCH MED,DEPT PHYSIOL & PHARMACOL,NOTTINGHAM NG7 2UH,ENGLAND

来源：

TOXICOLOGY | 1989年 / 54卷 / 01期

关键词：

D O I：

10.1016/0300-483X(89)90082-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：101 / 110

页数：10

共 27 条

[1] GLUTATHIONE DEPLETION BY ANILINE ANALOGS INVITRO ASSOCIATED WITH LIVER MICROSOMAL CYTOCHROME-P-450 [J].

AIKAWA, K ;

SATOH, T ;

KOBAYASHI, K ;

KITAGAWA, H .

JAPANESE JOURNAL OF PHARMACOLOGY, 1978, 28 (05) :699-705

[2] HEPATOTOXICITY DUE TO ALLYL ALCOHOL IN DEERMICE DEPENDS ON ALCOHOL-DEHYDROGENASE [J].

BELINSKY, SA ;

BRADFORD, BU ;

FORMAN, DT ;

GLASSMAN, EB ;

FELDER, MR ;

THURMAN, RG .

HEPATOLOGY, 1985, 5 (06) :1179-1182

[3]

BOYD MR, 1978, J PHARMACOL EXP THER, V207, P677

[4] MECHANISMS OF ACUTE HEPATIC TOXICITY - CHLOROFORM, HALOTHANE, AND GLUTATHIONE [J].

BROWN, BR ;

SIPES, IG ;

SAGALYN, AM .

ANESTHESIOLOGY, 1974, 41 (06) :554-561

[5]

BUCKPITT AR, 1984, J PHARMACOL EXP THER, V231, P291

[6] ALTERATIONS IN INTRACELLULAR THIOL HOMEOSTASIS DURING THE METABOLISM OF MENADIONE BY ISOLATED RAT HEPATOCYTES [J].

DIMONTE, D ;

ROSS, D ;

BELLOMO, G ;

EKLOW, L ;

ORRENIUS, S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1984, 235 (02) :334-342

[7]

DYROFF MC, 1983, MOL PHARMACOL, V23, P219

[8]

ESTERBAUER H, 1975, Z NATURFORSCH C, V30, P466

[9]

GORROD JW, 1981, TESTING TOXICITY, P77

[10] ENZYMATIC ACTIVATION OF CHEMICALS TO TOXIC METABOLITES [J].

GUENGERICH, FP ;

LIEBLER, DC .

CRC CRITICAL REVIEWS IN TOXICOLOGY, 1985, 14 (03) :259-307

← 1 2 3 →