CYTOTOXICITY OF AMALGAMS, ALLOYS, AND THEIR ELEMENTS AND PHASES

被引：40

作者：

KAGA, M ^{[1
]}

SEALE, NS ^{[1
]}

HANAWA, T ^{[1
]}

FERRACANE, JL ^{[1
]}

WAITE, DE ^{[1
]}

OKABE, T ^{[1
]}

机构：

[1] BAYLOR COLL DENT,DEPT DENT MAT,3302 GASTON AVE,DALLAS,TX 75246

来源：

DENTAL MATERIALS | 1991年 / 7卷 / 01期

关键词：

D O I：

10.1016/0109-5641(91)90031-S

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The purpose of this study was to compare the relative cytotoxicity of amalgams, alloys, and their constituent elements and phases, by means of a rapid and sensitive in vitro cell culture test. Pure copper and zinc showed intensive cytotoxicity, significantly greater than that of pure silver and mercury. Pure tin was non-cytotoxic. The gammaone phase (Ag2Hg3) revealed moderate cytotoxicity, which was significantly decreased by the addition of 1.5% and 5% Sn. However, the addition of 1.5% Zn to gamma-1 containing 1.5% Sn dramatically increased the cytotoxicity of gamma-1 to the same level as that of pure zinc. Whenever zinc was present in amalgams, higher cytotoxicity was revealed. High-copper amalgams showed the same cytotoxicity as a zinc-free low-copper amalgam. The addition of selenium did not reduce the cytotoxicity of amalgam. The cytotoxicity of amalgams was reduced after 24 h. The results of this study suggest that the major contributor to the cytotoxicity of alloy for amalgam is probably copper, while that for amalgam is zinc.

引用

页码：68 / 72

页数：5

共 33 条

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