THE COURSE OF VASOSPASM FOLLOWING SUBARACHNOID HEMORRHAGE IN RATS - A VERTEBROBASILAR ANGIOGRAPHIC STUDY

被引：26

作者：

VERLOOY, J ^{[1
]}

VANREEMPTS, J ^{[1
]}

HASELDONCKX, M ^{[1
]}

BORGERS, M ^{[1
]}

SELOSSE, P ^{[1
]}

机构：

[1] JANSSEN RES FDN,DEPT LIFE SCI,BEERSE,BELGIUM

来源：

ACTA NEUROCHIRURGICA | 1992年 / 117卷 / 1-2期

关键词：

SUBARACHNOID HEMORRHAGE; VASOSPASM; ANGIOGRAPHY; RAT BRAIN;

D O I：

10.1007/BF01400635

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The course of vasospasm following subarachnoid haemorrhage in rats was studied using vertebrobasilar angiography. Wistar and Sprague Dawley rats were compared with respect to vasospastic response after bleeding. A more pronounced vasospasm was found in Sprague Dawley rats. In order to avoid a possible toxic effect on the contrast medium, only one angiogram per animal was initially performed. However, a comparison with the results obtained in a separate series of non-challenged animals demonstrated a difficulty due to high variability in basilar artery size in the latter group. Therefore, vasospasm can be more readily shown if multiple angio-grams are used in the same animal so that the vasospasm can be expressed as a percentage of the initial diameter of the basilar artery. It was found that multiple angiograms are well tolerated when non-ionic contrast media are used.

引用

页码：48 / 52

页数：5

共 13 条

[1] CORTICAL EVOKED-POTENTIAL AND EXTRACELLULAR K+ AND H+ AT CRITICAL LEVELS OF BRAIN ISCHEMIA [J].