学术探索
学术期刊
新闻热点
数据分析
智能评审

MUCOSAL IMMUNITY TO INFECTION WITH IMPLICATIONS FOR VACCINE DEVELOPMENT

被引：172
作者：
STAATS, HF
JACKSON, RJ
MARINARO, M
TAKAHASHI, I
KIYONO, H
MCGHEE, JR
机构：
[1] OSAKA UNIV,SUITA,OSAKA 565,JAPAN
[2] UNIV ALABAMA,DEPT MICROBIOL,BIRMINGHAM,AL 35294
来源：
CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 04期
关键词：
D O I：
10.1016/0952-7915(94)90144-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The induction of effective mucosal immunity that also provides systemic immunity is a considerable challenge. Over the past two years, efforts to develop novel mucosal vaccine delivery systems to induce mucosal immunity against bacterial and viral diseases, including HIV, have dramatically increased. Here we cite novel vaccines and delivery systems being used to establish effective mucosal immunity.
引用
收藏
页码：572 / 583
页数：12
相关论文
共 69 条
  • [1] THE EXPRESSION OF HYBRID HIV-TY VIRUS-LIKE PARTICLES IN YEAST
    ADAMS, SE
    DAWSON, KM
    GULL, K
    KINGSMAN, SM
    KINGSMAN, AJ
    [J]. NATURE, 1987, 329 (6134) : 68 - 70
  • [2] HUMORAL AND CELL-MEDIATED IMMUNE-RESPONSES TO LIVE RECOMBINANT BCG-HIV VACCINES
    ALDOVINI, A
    YOUNG, RA
    [J]. NATURE, 1991, 351 (6326) : 479 - 482
  • [3] BERNSTEIN JM, 1994, HDB MUCOSAL IMMUNOLO, P625
  • [4] BOURGUIN I, 1991, FEMS MICROBIOL LETT, V81, P265, DOI 10.1111/j.1574-6968.1991.tb04770.x
  • [5] ORAL IMMUNIZATION WITH TOXOPLASMA-GONDII ANTIGENS IN ASSOCIATION WITH CHOLERA-TOXIN INDUCES ENHANCED PROTECTIVE AND CELL-MEDIATED-IMMUNITY IN C57BL/6 MICE
    BOURGUIN, I
    CHARDES, T
    BOUT, D
    [J]. INFECTION AND IMMUNITY, 1993, 61 (05) : 2082 - 2088
  • [6] Braciale T J, 1993, Trends Microbiol, V1, P323, DOI 10.1016/0966-842X(93)90069-4
  • [7] CARDENA L, 1991, 91ST GEN M AM SOC MI
  • [8] SYSTEMIC TOLERANCE AND SECRETORY IMMUNITY AFTER ORAL IMMUNIZATION
    CHALLACOMBE, SJ
    TOMASI, TB
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1980, 152 (06) : 1459 - 1472
  • [9] CONSTRUCTION OF A GENETICALLY DEFINED SALMONELLA-TYPHI TY2 AROA, AROC MUTANT FOR THE ENGINEERING OF A CANDIDATE ORAL TYPHOID TETANUS VACCINE
    CHATFIELD, SN
    FAIRWEATHER, N
    CHARLES, I
    PICKARD, D
    LEVINE, M
    HONE, D
    POSADA, M
    STRUGNELL, RA
    DOUGAN, G
    [J]. VACCINE, 1992, 10 (01) : 53 - 60
  • [10] USE OF THE NIRB PROMOTER TO DIRECT THE STABLE EXPRESSION OF HETEROLOGOUS ANTIGENS IN SALMONELLA ORAL VACCINE STRAINS - DEVELOPMENT OF A SINGLE-DOSE ORAL TETANUS VACCINE
    CHATFIELD, SN
    CHARLES, IG
    MAKOFF, AJ
    OXER, MD
    DOUGAN, G
    PICKARD, D
    SLATER, D
    FAIRWEATHER, NF
    [J]. BIO-TECHNOLOGY, 1992, 10 (08): : 888 - 892
1234567