LIQUID-LIQUID-EXTRACTION SYSTEMS FOR THC-COOH AND BENZOYLECGONINE

被引：11

作者：

NEEDLEMAN, SB ^{[1
]}

GOODIN, K ^{[1
]}

SEVERINO, W ^{[1
]}

机构：

[1] ST JOHNS UNIV,COLLEGEVILLE,MN 56321

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1991年 / 15卷 / 04期

关键词：

D O I：

10.1093/jat/15.4.179

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Because DuPont Instruments has discontinued commercial availability of the PREP automated sample processor, an alternate method for the general extraction of THC-COOH and benzoylecgonine from a urine matrix in the military drug screening laboratories' standard procedure is needed. The liquid-liquid extraction method presented for isolation of THC-COOH uses extraction with isobutanol-hexane followed by back extraction into an aqueous alkaline medium and results in a percent recovery of 104.24 +/- 9.71%. The isolation of benzoylecgonine involves extraction into ethanol-methylene chloride followed by evaporation and derivatization with 1-iodopropane; recovery is 102.43 +/- 3.13%.

引用

页码：179 / 181

页数：3