SEXUAL STAGE DEVELOPMENT OF CRYPTOSPORIDIA IN THE CACO-2 CELL-LINE

被引：49

作者：

BURAUD, M

FORGET, E

FAVENNEC, L

BIZET, J

GOBERT, JG

DELUOL, AM

机构：

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 12期

关键词：

D O I：

10.1128/IAI.59.12.4610-4613.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We used the spontaneously differentiated human intestinal epithelial cell line Caco-2 to develop an in vitro model of Cryptosporidium sp. infection. The mean cell infection rate was 3% +/- 2%. Asexual stages of cryptosporidia were observed on day 2 postinoculation. Transmission electron microscopy showed the presence of macrogametes at day 5. This cell line appears to be suited to the study of the mechanisms by which biological agents inhibit both sexual and asexual development of cryptosporidia.

引用

页码：4610 / 4613

页数：4

共 12 条

[1] ISOLATION OF CRYPTOSPORIDIUM OOCYSTS AND SPOROZOITES USING DISCONTINUOUS SUCROSE AND ISOPYCNIC PERCOLL GRADIENTS
ARROWOOD, MJ
STERLING, CR
[J]. JOURNAL OF PARASITOLOGY, 1987, 73 (02) : 314 - 319
[2] INVITRO DEVELOPMENT OF ASEXUAL STAGES OF CRYPTOSPORIDIUM SP IN CELL-CULTURE
BONNIN, A
SALIMBENI, I
DUBREMETZ, JF
HARLY, G
CHAVANET, P
CAMERLYNCK, P
[J]. ANNALES DE PARASITOLOGIE HUMAINE ET COMPAREE, 1990, 65 (01): : 41 - 43
[3] COMPLETE DEVELOPMENT OF CRYPTOSPORIDIUM IN CELL-CULTURE
CURRENT, WL
HAYNES, TB
[J]. SCIENCE, 1984, 224 (4649) : 603 - 605
[4] DEVELOPMENT OF HUMAN AND CALF CRYPTOSPORIDIUM IN CHICKEN EMBRYOS
CURRENT, WL
LONG, PL
[J]. JOURNAL OF INFECTIOUS DISEASES, 1983, 148 (06) : 1108 - 1113
[5] COMPLETE DEVELOPMENT OF CRYPTOSPORIDIUM INVITRO - APPLICATIONS
DATRY, A
DANIS, M
GENTILINI, M
[J]. M S-MEDECINE SCIENCES, 1989, 5 (10): : 762 - 766
[6] DATRY A, 1986, 2ND INT C ACQ IMM SY
[7] ASEXUAL DEVELOPMENT OF CRYPTOSPORIDIUM-PARVUM WITHIN A DIFFERENTIATED HUMAN ENTEROCYTE CELL-LINE
FLANIGAN, TP
AJI, T
MARSHALL, R
SOAVE, R
AIKAWA, M
KAETZEL, C
[J]. INFECTION AND IMMUNITY, 1991, 59 (01) : 234 - 239
[8] INVITRO CULTIVATION OF CRYPTOSPORIDIUM-PARVUM AND SCREENING FOR ANTICRYPTOSPORIDIAL DRUGS
MCDONALD, V
STABLES, R
WARHURST, DC
BARER, MR
BLEWETT, DA
CHAPMAN, HD
CONNOLLY, GM
CHIODINI, PL
MCADAM, KPWJ
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1990, 34 (08) : 1498 - 1500
[9] CRYPTOSPORIDIUM SP OF THE STARRED LIZARD AGAMA-STELLIO - ULTRASTRUCTURE AND LIFE-CYCLE
OSTROVSKA, K
PAPERNA, I
[J]. PARASITOLOGY RESEARCH, 1990, 76 (08) : 712 - 720
[10] PINTO M, 1983, BIOL CELL, V47, P323

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