RHABDOMYOLYSIS AFTER SUICIDAL INGESTION OF AN OVERDOSE OF CAFFEINE, ACETAMINOPHEN AND PHENAZONE AS A FIXED-DOSE COMBINATION (SPALT-N)

被引：14

作者：

MICHAELIS, HC

SHARIFI, S

SCHOEL, G

机构：

[1] UNIV GOTTINGEN,DEPT CLIN PHARMACOL,W-3400 GOTTINGEN,GERMANY

[2] UNIV GOTTINGEN,DEPT INTERNAL MED,W-3400 GOTTINGEN,GERMANY

来源：

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 1991年 / 29卷 / 04期

关键词：

D O I：

10.3109/15563659109025750

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Rhabdomyolysis without renal failure was noted after suicidal ingestion of 29 tablets of Spalt N containing 7.25 g of acetaminophen, 7.25 g of phenazone and 1.45 g of caffeine by a 29 year-old weighing 73 kg. The maximum serum creatine kinase was 1920 U/L, serum myoglobins were 49 to 167 ng/mL. Acetaminophen, phenazone and caffeine were quantified and identified in serum by gas chromatography and gas chromatography/mass spectrometry. It is suggested that rhabdomyolysis might have been caused by caffeine.

引用

页码：521 / 526

页数：6

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