TISSUE-SPECIFIC RESPONSE OF ESTROGEN-RECEPTOR GENE-EXPRESSION TO ESTROGEN IN CHICK

被引：20

作者：

NINOMIYA, Y

MOCHII, M

EGUCHI, G

HASEGAWA, T

MASUSHIGE, S

KATO, S

机构：

[1] TOKYO UNIV AGR, FAC AGR, DEPT AGR CHEM, SETAGAYA KU, TOKYO 156, JAPAN

[2] NATL INST BASIC BIOL, OKAZAKI, AICHI 444, JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 187卷 / 03期

关键词：

D O I：

10.1016/0006-291X(92)90454-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed a sensitive assay system by RT(reverse transcription)-PCR(polymerase chain reaction) to detect the low level of chicken estrogen receptor (cER) transcript. Using this system, the differential expression of cER gene in chick tissues was observed. Moreover, we found that the oviduct cER transcript levels in chick was not affected, albeit the remarkable growth of this tissue, by exogenous estrogen. In contrast, estrogen enhanced the hepatic cER transcript level several folds. Thus, the present study clearly showed a novel tissue-specific response of cER gene expression to estrogen in chick. © 1992.

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页码：1374 / 1380

页数：7

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