POTENTIAL ANTI-TUMOR AGENTS .36. QUANTITATIVE RELATIONSHIPS BETWEEN EXPERIMENTAL ANTI-TUMOR ACTIVITY, TOXICITY, AND STRUCTURE FOR THE GENERAL-CLASS OF 9-ANILINOACRIDINE ANTI-TUMOR AGENTS

被引：197

作者：

DENNY, WA ^{[1
]}

CAIN, BF ^{[1
]}

ATWELL, GJ ^{[1
]}

HANSCH, C ^{[1
]}

PANTHANANICKAL, A ^{[1
]}

LEO, A ^{[1
]}

机构：

[1] POMONA COLL,DEPT CHEM,CLAREMONT,CA 91711

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 03期

关键词：

D O I：

10.1021/jm00345a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

引用

页码：276 / 315

页数：40

共 59 条

[1]

THE IONISATION OF ACRIDINE BASES [J].

ALBERT, A ;

GOLDACRE, R .

JOURNAL OF THE CHEMICAL SOCIETY, 1946, (AUG) :706-713

[2]

POTENTIAL ANTITUMOR AGENTS .22. LATENTIATED CONGENERS OF 4'-(9-ACRIDINYLAMINO)METHANESULFONANILIDES [J].

ATWELL, GJ ;

CAIN, BF ;

DENNY, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (04) :520-526

[3]

POTENTIAL ANTITUMOR AGENTS .12. 9-ANILINOACRIDINES [J].

ATWELL, GJ ;

CAIN, BF ;

SEELYE, RN .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (06) :611-&

[4]

POTENTIAL ANTITUMOR AGENTS .24. DI-CATIONIC ANALOGS OF 4'-(9-ACRIDINYLAMINO)ALKANESULFONANILIDES [J].

ATWELL, GJ ;

CAIN, BF ;

DENNY, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (09) :1128-1134

[5]

ATWELL GJ, UNPUB

[6]

POTENTIAL ANTI-TUMOR AGENTS .35. QUANTITATIVE RELATIONSHIPS BETWEEN ANTI-TUMOR (L1210) POTENCY AND DNA-BINDING FOR 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE ANALOGS [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) :520-525

[7]

POTENTIAL ANTI-TUMOR AGENTS .34. QUANTITATIVE RELATIONSHIPS BETWEEN DNA-BINDING AND MOLECULAR-STRUCTURE FOR 9-ANILINOACRIDINES SUBSTITUTED IN THE ANILINO RING [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (02) :170-177

[8]

BARCLAY IM, 1941, J CHEM SOC, P117

[9]

POTENTIAL ANTITUMOR AGENTS .21. DIALKANOLAMINE DIALKANESULFONIC ESTERS [J].

CAIN, BF ;

DENNY, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (04) :515-520

[10]

POTENTIAL ANTITUMOR AGENTS .20. STRUCTURE-ACTIVITY-SITE RELATIONSHIPS FOR 4'-(9-ACRIDINYLAMINO)ALKANESULFONANILIDES [J].

CAIN, BF ;

ATWELL, GJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (12) :1409-1416

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