CORNEAL DECOMPENSATION IN MITOCHONDRIAL OPHTHALMOPLEGIA PLUS (KEARNS-SAYRE) SYNDROME - A CLINICOPATHOLOGICAL CASE-REPORT

被引：22

作者：

CHANG, TS ^{[1
]}

JOHNS, DR ^{[1
]}

STARK, WJ ^{[1
]}

DRACHMAN, DB ^{[1
]}

GREEN, WR ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV HOSP,EYE PATHOL LAB,BALTIMORE,MD 21287

来源：

CORNEA | 1994年 / 13卷 / 03期

关键词：

CLINICOPATHOLOGICAL CORRELATION; CORNEAL DECOMPENSATION; ELECTRON MICROSCOPY; KEARNS-SAYRE SYNDROME; MITOCHONDRIA; MITOCHONDRIAL ENCEPHALOMYOPATHY; PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; OPHTHALMOPLEGIA PLUS;

D O I：

10.1097/00003226-199405000-00014

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The authors describe the clinical, molecular genetic, and pathologic findings of a patient with corneal decompensation associated with the mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. Ultrastructurally abnormal mitochondria were observed and possibly implicate this organelle in the pathogenesis of corneal edema.

引用

页码：269 / 273

页数：5