POLYMORPHIC TANDEM REPEAT REGION IN INTERLEUKIN-1-ALPHA INTRON-6

被引：26

作者：

BAILLY, S ^{[1
]}

DIGIOVINE, FS ^{[1
]}

DUFF, GW ^{[1
]}

机构：

[1] UNIV SHEFFIELD,ROYAL HALLAMSHIRE HOSP,DEPT MED,MOLEC MED SECT,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND

来源：

HUMAN GENETICS | 1993年 / 91卷 / 01期

关键词：

D O I：

10.1007/BF00230231

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Analysis of polymerase chain reaction amplified products from the sixth intron of the human interleukin-1-alpha gene reveals a high polymorphism (polymorphism information content = 0.51) in a Caucasian population. Altogether, seven alleles have been defined ranging from 620 to 1220bp. This polymorphism is probably attributable to a variable number of 46-bp tandem repeats, each containing potential regulatory sequences.

引用

页码：85 / 86

页数：2

共 5 条

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