MECHANICAL PLUS PHARMACOLOGICAL PROPHYLAXIS FOR DEEP-VEIN THROMBOSIS IN ACUTE SPINAL-CORD INJURY

被引：48

作者：

MERLI, GJ

CRABBE, S

DOYLE, L

DITUNNO, JF

HERBISION, GJ

机构：

[1] Department of Medicine, Philadelphia, PA, 19107, 2115 9th Street

[2] Department of Pharmacy, Philadelphia, PA, 19107, 2115 9th Street

[3] Department of Rehabilitation Medicine, Thomas Jefferson University Hospital, Regional Spinal Cord Injury Center of the Delaware Valley, Philadelphia, PA, 19107, 2115 9th Street

来源：

PARAPLEGIA | 1992年 / 30卷 / 08期

关键词：

DEEP VEIN THROMBOSIS; SPINAL CORD INJURY; PROPHYLAXIS; MECHANICAL AND PHARMACOLOGICAL;

D O I：

10.1038/sc.1992.115

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This pilot study assessed the effectiveness of external pneumatic compression (EPC) with gradient elastic stockings (GES) and low dose heparin (LDH) in the prevention of deep vein thrombosis (DVT) in acute spinal cord injured (SCI) patients in the first 14 days following injury. Twenty-one consecutive patients within 48 hrs of injury with acute C2 through T12 motor complete or nonfunctional motor incomplete spinal cord-lesions were enrolled. 125 1 fibrinogen scanning was performed daily. A positive scan was confirmed by venography. Thrombosis was demonstrated in 1/19 patients. A control group from a previous study confirmed thrombosis in 6/17 patients (p = 0.04). Comparison of extent of thrombosis demonstrated a reduction in the treated group (p = 0.02). This pilot study demonstrates that EPC with GES plus LDH may be an effective prophylactic regimen in these patients.

引用

页码：558 / 562

页数：5

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