SPECTROPHOTOMETRIC ANALYSIS OF A PHARMACEUTICAL PREPARATION BY PRINCIPAL COMPONENT REGRESSION

被引：29

作者：

BLANCO, M

COELLO, J

GONZALEZ, F

ITURRIAGA, H

MASPOCH, S

机构：

[1] Departament de Química, Unitat de Química Analítica, Universitat Autònoma de Barcelona, Bellaterra

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1993年 / 82卷 / 08期

关键词：

D O I：

10.1002/jps.2600820816

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC.

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页码：834 / 837

页数：4

相关论文

共 18 条

[1] MULTICOMPONENT SPECTROPHOTOMETRIC ASSAY OF RIBOFLAVIN AND PHOTOPRODUCTS [J].

AHMAD, I ;

RAPSON, HDC .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1990, 8 (03) :217-223

[2] APPLICATION OF A PHOTODIODE ARRAY DETECTOR TO MULTICOMPONENT DETERMINATION BY FLOW-INJECTION ANALYSIS [J].

BLANCO, M ;

GENE, J ;

ITURRIAGA, H ;

MASPOCH, S .

ANALYST, 1987, 112 (05) :619-622

[3] THE IMPORTANCE OF EXTINCTION RATIOS IN THE SPECTROPHOTOMETRIC ANALYSIS OF MIXTURES OF 2 KNOWN ABSORBING SUBSTANCES [J].

GLENN, AL .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1960, 12 (10) :595-608

[4] SIMULTANEOUS DETERMINATION OF TRIGLYCERIDES, PHOSPHOLIPIDS, AND CHOLESTERYL ESTERS BY INFRARED SPECTROMETRY [J].

KISNER, HJ ;

BROWN, CW ;

KAVARNOS, GJ .

ANALYTICAL CHEMISTRY, 1982, 54 (09) :1479-1485

[5] APPLICATION OF KALMAN FILTER SPECTROPHOTOMETRY IN THE ANALYSIS OF PHARMACEUTICAL PREPARATIONS .1. SULFAMETHOXYPYRAZINE AND TRIMETHROPRIM IN SULPHA COMPOUND TABLETS [J].

LUO, GA ;

QUI, JX ;

WANG, YM ;

YU, ZW .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1989, 7 (04) :507-511

[6]

Martens H, 1989, MULTIVARIATE CALIBRA

[7] 2ND-DERIVATIVE SPECTROPHOTOMETRIC ASSAY OF MIXTURES OF DICLOXACILLIN SODIUM AND AMPICILLIN-SODIUM IN PHARMACEUTICALS [J].

MORELLI, B .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1988, 77 (12) :1042-1046

[8]

NOWICKAJANKOWSK.T, 1986, COMPREHENSIVE ANAL C, V15, pCH7

[9] NUMERICAL ERROR ANALYSIS OF DERIVATIVE SPECTROMETRY FOR QUANTITATIVE-ANALYSIS OF MIXTURES [J].

OHAVER, TC ;

GREEN, GL .

ANALYTICAL CHEMISTRY, 1976, 48 (02) :312-318

[10] DERIVATIVE AND WAVELENGTH MODULATION SPECTROMETRY [J].

OHAVER, TC .

ANALYTICAL CHEMISTRY, 1979, 51 (01) :A91-&