ADVANTAGES AND LIMITATIONS OF MASS SPECTROMETRIC SEQUENCE DETERMINATION OF PERMETHYLATED OLIGOPEPTIDE DERIVATIVES

被引:54
作者
THOMAS, DW
DAS, BC
GERO, SD
LEDERER, E
机构
关键词
D O I
10.1016/0006-291X(68)90369-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The mass spectrometric sequence determination of O,N-permethylated oligopeptide derivatives can be extremely facile because their spectra consist principally of peaks arising from CO-NCH3 cleavage. In addition, the increased volatility resulting after permethylation has permitted even compounds as large as pentadecapeptide derivatives to be analyzed by this method. © 1968.
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页码:199 / &
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