EFFECTS OF PRETREATMENT WITH BENZO[A]PYRENE ON THE STEREOCHEMICAL SELECTIVITY OF METABOLIC-ACTIVATION OF BENZO[A]PYRENE TO DNA-BINDING METABOLITES IN HAMSTER-EMBRYO CELL-CULTURES

被引：9

作者：

SMOLAREK, TA ^{[1
]}

MORGAN, SL ^{[1
]}

KELLEY, J ^{[1
]}

BAIRD, WM ^{[1
]}

机构：

[1] PURDUE UNIV,SCH PHARM & PHARMACAL SCI,DEPT MED CHEM & PHARMACOGNOSY,W LAFAYETTE,IN 47907

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1987年 / 64卷 / 1-2期

关键词：

D O I：

10.1016/0009-2797(87)90061-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：71 / 82

页数：12

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CONNEY, AH .

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[4]

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[5]

HARVEY RG, 1984, ACS S SERIES, V283

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Jerina D M, 1986, Adv Exp Med Biol, V197, P11

[7]

MILNER JA, 1985, CANCER RES, V45, P6347

[8]

MOORE PD, 1977, DRUG METABOLISM CONC, P127

[9] P450 GENES - STRUCTURE, EVOLUTION, AND REGULATION [J].

NEBERT, DW ;

GONZALEZ, FJ .

ANNUAL REVIEW OF BIOCHEMISTRY, 1987, 56 :945-993

[10]

NEBERT DW, 1968, J BIOL CHEM, V243, P6250

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