MICROBIAL MUTAGENICITY OF STREPTOZOTOCIN IN ANIMAL-MEDIATED ASSAYS

被引：51

作者：

GABRIDGE, MG

DENUNZIO, A

LEGATOR, MS

机构：

[1] Cell Biology Branch, Bureau of Science, Food and Drug Administration

来源：

NATURE | 1969年 / 221卷 / 5175期

关键词：

D O I：

10.1038/221068a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

STREPTOZOTOCIN, a broad spectrum antibiotic with a unique structure (glucose-NHCON(NO)CH3), has several interesting properties. It is diabetogenic, carcinogenic, carcinostatic and phage-inducing1-4. It has recently been shown to be mutagenic for Salmonella typhimurium in vitro5. © 1969 Nature Publishing Group.

引用

页码：68 / +

页数：1

共 8 条

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[5] KOLBYE S, IN PRESS
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[8] TUMOUR PRODUCTION IN GLANDULAR STOMACH OF RAT BY N-METHYL-N'-NITRO-N-NITROSOGUANIDINE
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