PREPARATION OF RE-186 LABELED EHDP AND ITS POSSIBLE USE IN THE TREATMENT OF OSSEOUS NEOPLASMS

被引:58
作者
MATHIEU, L [1 ]
CHEVALIER, P [1 ]
GALY, G [1 ]
BERGER, M [1 ]
机构
[1] HOSP CIVILS LYON,CTR MED NUCL,F-69394 LYON 3,FRANCE
来源
INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1979年 / 30卷 / 12期
关键词
D O I
10.1016/0020-708X(79)90150-9
中图分类号
TL [原子能技术]; O571 [原子核物理学];
学科分类号
0827 ; 082701 ;
摘要
EHDP is known to be markedly concentrated in bone. Labelled with 99mTc, it is routinely used radiopharmaceutical for bone scanning. From the similarity of rhenium and technetium chemical properties, EHDP might be labelled with 186Re. The physical properties of this isotope are convenient for β-therapy and its γ-emission allows its external detection. This communication describes the preparation of 186Re labelled EHDP and the bone seeking of this agent in rat, as seen by external scanning. © 1979.
引用
收藏
页码:725 / 727
页数:3
相关论文
共 12 条