SWEDISH DIOXIN SURVEY - DETERMINATION OF 2,3,7,8-TCDD TOXIC EQUIVALENT FACTORS FOR SOME POLYCHLORINATED-BIPHENYLS AND NAPHTHALENES USING BIOLOGICAL TESTS

被引：131

作者：

HANBERG, A

WAERN, F

ASPLUND, L

HAGLUND, E

SAFE, S

机构：

[1] NATL ENVIRONM PROTECT BOARD,SPECIAL ANALYT LAB,S-17125 SOLNA,SWEDEN

[2] UNIV STOCKHOLM,WALLENBERG LAB,S-10691 STOCKHOLM,SWEDEN

[3] TEXAS A&M UNIV SYST,DEPT VET PHYSIOL & PHARMACOL,COLLEGE STN,TX 77843

来源：

CHEMOSPHERE | 1990年 / 20卷 / 7-9期

关键词：

AHH; enzyme induction; EROD; PCB; PCN; Swedish Dioxin Survey;

D O I：

10.1016/0045-6535(90)90238-O

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In order to find out which compounds to include in the analytical protocol in the Swedish Dioxin Survey, available co-planar polychlorinated biphenyl (pPCB) and naphthalene (PCN) congeners have been tested in two enzyme induction assays. The results show that the polychlorinated naphthalenes seems to be about as active as enzyme inducers as certain coplanar PCBs. © 1990.

引用

页码：1161 / 1164

页数：4

共 11 条

[1] CHARACTERIZATION OF A STRONGLY BIOACCUMULATING HEXACHLORONAPHTHALENE
ASPLUND, L
JANSSON, B
SUNDSTROM, G
BRANDT, I
BRINKMAN, UAT
[J]. CHEMOSPHERE, 1986, 15 (05) : 619 - 628
[2] POLYCHLORINATED DIBENZOFURANS (PCDFS) - EFFECTS OF STRUCTURE ON BINDING TO THE 2,3,7,8-TCDD CYTOSOLIC RECEPTOR PROTEIN, AHH INDUCTION AND TOXICITY
BANDIERA, S
SAWYER, T
ROMKES, M
ZMUDZKA, B
SAFE, L
MASON, G
KEYS, B
SAFE, S
[J]. TOXICOLOGY, 1984, 32 (02) : 131 - 144
[3] BRADFIELD CA, 1988, MOL PHARMACOL, V34, P229
[4] HEPTACHLORONAPHTHALENE, HEXACHLORONAPHTHALENE, TETRACHLORONAPHTHALENE AND DICHLORONAPHTHALENE CONGENERS AS INDUCERS OF HEPATIC-MICROSOMAL DRUG-METABOLIZING-ENZYMES
CAMPBELL, MA
BANDIERA, S
ROBERTSON, L
PARKINSON, A
SAFE, S
[J]. TOXICOLOGY, 1983, 26 (3-4) : 193 - 205
[5] POLYCHLORINATED NAPHTHALENES AS HEPATIC MICROSOMAL-ENZYME INDUCERS IN THE IMMATURE MALE-RAT
COCKERLINE, R
SHILLING, M
SAFE, S
[J]. GENERAL PHARMACOLOGY, 1981, 12 (02): : 83 - 87
[6] SYNTHESIS OF HEXACHLORONAPHTHALENE AND HEPTACHLORONAPHTHALENES
HAGLUND, E
BERGMAN, A
[J]. CHEMOSPHERE, 1989, 19 (1-6) : 195 - 200
[7] JANSSON B, 1984, CHEMOSPHERE, V13, P33, DOI 10.1016/0045-6535(84)90006-7
[8] NEBERT DW, 1968, J BIOL CHEM, V243, P6242
[9] A RAPID METHOD FOR ASSAYING THE METABOLISM OF 7-ETHOXYRESORUFIN BY MICROSOMAL SUBCELLULAR-FRACTIONS
POHL, RJ
FOUTS, JR
[J]. ANALYTICAL BIOCHEMISTRY, 1980, 107 (01) : 150 - 155
[10] PCB ISOMERS AND CONGENERS - INDUCTION OF ARYL-HYDROCARBON HYDROXYLASE AND ETHOXYRESORUFIN O-DEETHYLASE ENZYME-ACTIVITIES IN RAT HEPATOMA-CELLS
SAWYER, T
SAFE, S
[J]. TOXICOLOGY LETTERS, 1982, 13 (1-2) : 87 - 93

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