STEREOCONTROLLED INTRAMOLECULAR CYCLIZATION OF OMEGA-TRIBUTYLSTANNYL ETHER ALDEHYDES - SYNTHESIS OF THE 6.7.7.6 RING-SYSTEM OF POLYCYCLIC ETHERS

被引：74

作者：

YAMAMOTO, Y

YAMADA, J

KADOTA, I

机构：

[1] Department of Chemistry, Faculty of Science, Tohoku University, Sendai

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 48期

关键词：

D O I：

10.1016/0040-4039(91)85042-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The BF3.OEt2 mediated intramolecular cyclization of the gamma-oxo-substituted allylic tin (1) having an aldehyde group at the terminus of the carbon chain proceeded in a stereocontrolled manner to give the 7-membered beta-hydroxy cyclic ether (2a) with high diastereoselectivity. This method was applied for the synthesis of the 6.7.7.6 ring system (3a).

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页码：7069 / 7072

页数：4

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