DIAGRAMMATIC REPRESENTATION OF THE DISTRIBUTION OF DNA BASES AND ITS APPLICATIONS

被引:9
作者
ZHANG, CT [1 ]
ZHANG, R [1 ]
机构
[1] SHANGHAI MED UNIV,DEPT PUBL HLTH,SHANGHAI,PEOPLES R CHINA
关键词
REGULAR TETRAHEDRON; MAPPING; DNA BASES;
D O I
10.1016/0141-8130(91)90009-J
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The frequencies of occurrence of the bases A, C, G and T (or U) in a DNA or mRNA sequence are denoted by a, c, g, t (or u), respectively. Since a + c + g + t = 1, the four real numbers are mapped into a point within a regular tetrahedron. The mapping points are then projected to some planes for further study. We have given several examples of application of this technique. As a by-product of an application we have found an empirical formula on the limit distribution of DNA bases for different kind of organisms, i.e. 1/4 less-than-or-equal-to a2 + c2 + g2 + t2 < 1/3.
引用
收藏
页码:45 / 49
页数:5
相关论文
共 7 条
[1]  
BUCHANAN RE, 1974, BERGEYS MANUAL DETER, pCH15
[2]  
LASKIN AI, 1981, CRC HDB MICROBIOLOGY, V3
[3]  
Sober H.A., 1970, HDB BIOCH SELECTED D, Vsecond
[5]  
TRIFONOV EN, 1989, J MOL BIOL, V138, P457
[6]   THE STUDY OF DNA-SEQUENCES BY THEIR SEQUENCES OF TWIST ANGLES [J].
ZHANG, CT ;
CEN, YQ .
JOURNAL OF THEORETICAL BIOLOGY, 1989, 138 (04) :457-465
[7]  
ZHANG CT, 1990, J THEOR BIOL, V142, P218