PLASMA COMPLEMENT AND HISTAMINE CHANGES IN ATOPIC-DERMATITIS

被引：43

作者：

RING, J

SENTER, T

CORNELL, RC

ARROYAVE, CM

TAN, EM

机构：

[1] SCRIPPS CLIN & RES FDN,DIV DERMATOL,LA JOLLA,CA 92037

[2] SCRIPPS CLIN & RES FDN,DIV ALLERGY & IMMUNOL,LA JOLLA,CA 92037

[3] UNIV COLORADO,MED CTR,DIV DERMATOL,DENVER,CO 80202

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1979年 / 100卷 / 05期

关键词：

D O I：

10.1111/j.1365-2133.1979.tb05577.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Fifteen patients with atopic dermatitis were investigated to evaluate the total of complement and histamine. In five patients total serum complement haemolytic activity (CH50) was significantly decreased as was the haemolytic activity of complement components C2 (C2H50) and C3 (C3H50) By counter immunoelectrophoresis split products of C3 were detected. There was no evidence for alternative pathway activation or the presence of an activator of the alternative pathway. In three patients plasma histamine concetrations were elevated. The intensity of the complement and histamine changes observed seemed to be correlated to the severity of the disease. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：521 / 530

页数：10

共 52 条

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