Population-based genetic screening

被引：31

作者：

Cao, Antonio ^{[1
]}

Rosatelli, Maria Cristina ^{[1
]}

Galanello, Renzo ^{[1
]}

机构：

[1] Univ Cagliari, Inst Clin & Biol Eta Evolut, Via Jenner S-N, I-09100 Cagliari, Italy

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-437X(91)80040-S

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A preventive genetic programme aimed to control beta-thalassemia in the Sardinian population is based on a combination of increased awareness of the population, carrier screening, genetic counselling and prenatal diagnosis. As a result, the registry of thalassemia major demonstrated a profound decline in the incidence of this disease from 1 per 250 to 1 per 1200 live births, with 90% of cases effectively prevented.

引用

页码：48 / 53

页数：6

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