PAIN RELIEF AFTER INGUINAL-HERNIA REPAIR - A RANDOMIZED DOUBLE-BLIND-STUDY

被引:34
作者
NEHRA, D [1 ]
GEMMELL, L [1 ]
PYE, JK [1 ]
机构
[1] MAELOR GEN HOSP, DEPT SURG, WREXHAM LL13 7TD, CLWYD, WALES
关键词
D O I
10.1002/bjs.1800820929
中图分类号
R61 [外科手术学];
学科分类号
摘要
A randomized double-blind study was undertaken using 0.5 per cent bupivacaine ilioinguinal field block and oral papaveretum-aspirin tablets to assess pain relief after hernia surgery. A consecutive series of 200 men undergoing repair of a unilateral inguinal hernia underwent random allocation into one of the four groups to receive: bupivacaine and papaveretum-aspirin (group 1), bupivacaine and oral placebo (group 2), saline and papaveretum-aspirin (group 3), or saline and oral placebo (group 4). Patients were prescribed postoperative opiates to be given on demand. Pain levels and mobility were A assessed at 6 and 24 h after operation. Patients in group 1 reported significantly less pain, required less additional opiates and had better mobility than those in group 4 (pain score P<0.001 at 6 h and P=0.002 at 24 h) and group 3 (P=0.002 for pain and mobility scores at 6 h). Bupivacaine alone provided good immediate postoperative pain relief (P=0.002 group 2 versus group 4 at 6 h). The combination of bupivacaine and papaveretum-aspirin provided the best results and is suitable for day-case postoperative analgesia.
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页码:1245 / 1247
页数:3
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