ONTOGENY, CELL DISTRIBUTION, AND THE PHYSIOLOGICAL-ROLE OF NADP-MALIC ENZYME IN DROSOPHILA-MELANOGASTER

被引：42

作者：

GEER, BW ^{[1
]}

KROCHKO, D ^{[1
]}

WILLIAMSON, JH ^{[1
]}

机构：

[1] UNIV CALGARY,DEPT BIOL,CALGARY T2N 1N4,ALBERTA,CANADA

来源：

BIOCHEMICAL GENETICS | 1979年 / 17卷 / 9-10期

关键词：

development; Drosophila; malic enzyme; NADP enzymes; nutrition;

D O I：

10.1007/BF00504309

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

NADP-malic enzyme (NADP-ME) (E.C. 1.1.1.40) is situated in the cytosol of Drosophila melanogaster. Both the tissue activity and CRM level of NADP-ME parallel changes in the dosage of a gene, Men+, located in region 87C2-3 to 87D1-2 of the third chromosome. The tissue activity of NADP-ME is very high in early third instar larvae, providing about 33% of the NADPH at this life stage. The tissue activity declines during pupal development but increases as the adult ages. The concentration of NADP-ME CRM and tissue activity are coordinately increased in third instar larvae by dietary carbohydrate and decreased by dietary lipid. © 1979 Plenum Publishing Corporation.

引用

页码：867 / 879

页数：13

共 36 条

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[2]

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