SILYL-CUPRATION OF AN ACETYLENE FOLLOWED BY RING-FORMATION

被引：8

作者：

FLEMING, I

DEMARIGORTA, EM

机构：

[1] University Chemical Laboratory, Cambridge, CB2 1EW, Lensfield Road

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)77528-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The acetylenes 1a-e undergo silyl-cupration followed by cyclisation, the acetylenes 1f-1h react with the silyl-cuprate reagent more rapidly at the alternative electrophilic site, and the acetylenes 1i, 1j and 21 give relatively low yields of cyclic products amongst others. Ring-formation is, unusually, a not particularly favourable pathway.

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页码：1201 / 1204

页数：4

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