PHENTOLAMINE - USE IN DIGITALIS-INDUCED ARRHYTHMIAS - CANINE EXPERIMENTS

被引：24

作者：

ETTINGER, S

GOULD, L

CARMICHAEL, JA

TASHJIAN, RJ

机构：

来源：

AMERICAN HEART JOURNAL | 1969年 / 77卷 / 05期

关键词：

D O I：

10.1016/0002-8703(69)90548-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The antiarrhythmic effect of phentolamine was investigated in 10 normal dogs acutely digitalized with ouabain. Phentolamine was infused intravenously for an average of 10 minutes at 0.3 mg. per minute. Ventricular arrhythmias were abolished in 7 of 8 cases (there was complete heart block in 1 case), and the rate was increased in one case with sinus bradycardia. Administration of the drug produced no untoward side effects and did not produce hypotension. These studies indicate that phentolamine may be of clinical value as an antiarrhythmic agent and warrants further study. © 1969.

引用

页码：636 / +

页数：1