INHERITANCE OF PIM SUBTYPES - STUDY OF 151 FAMILIES WITH A TOTAL OF 242 CHILDREN AND OF 142 MOTHER-CHILD PAIRS

被引：16

作者：

CLEVE, H ^{[1
]}

PATUTSCHNICK, W ^{[1
]}

STRECKER, K ^{[1
]}

NEVO, S ^{[1
]}

机构：

[1] HAIFA UNIV,HAIFA,ISRAEL

来源：

HUMAN HEREDITY | 1979年 / 29卷 / 06期

关键词：

D O I：

10.1159/000153071

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Pi phenotypes were classified by isoelectric focusing in sera of 151 families with a total of 242 children and in sera of 142 mother-child pairs. The 6 common subtypes of PiM are genetically determined by 3 alleles named Pi(M1), Pi(M2), and Pi(M3). No exceptions to the postulated mode of inheritance have been found. The possibility of further heterogeneity of the intermediate variant PiM3 is discussed.

引用

页码：351 / 354

页数：4

共 10 条

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[8] POPULATION-GENETICS OF ALPHA1-ANTITRYPSIN IN NETHERLANDS - DESCRIPTION OF A NEW ELECTROPHORETIC VARIANT
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