ISOLATION OF 9-DIHYDRO-13-ACETYLBACCATIN-III FROM TAXUS-CANADENSIS

被引：57

作者：

GUNAWARDANA, GP

PREMACHANDRAN, U

BURRES, NS

WHITTERN, DN

HENRY, R

SPANTON, S

MCALPINE, JB

机构：

[1] Pharmaceutical Products Research and Development, Abbott Laboratories, Illinois 60064, Abbott Park

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 11期

关键词：

D O I：

10.1021/np50089a022

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The investigation of Taxus canadensis (Canada yew) needles as a renewable source of taxol and its congeners led to the isolation of a novel taxane derivative, 9-dihydro-13-acetylbaccatin III[1], which was characterized by spectral analyses and confirmed by single crystal X-ray diffraction studies.

引用

页码：1686 / 1689

页数：4

共 17 条

[1] H-1 AND C-13 ASSIGNMENTS FROM SENSITIVITY-ENHANCED DETECTION OF HETERONUCLEAR MULTIPLE-BOND CONNECTIVITY BY 2D MULTIPLE QUANTUM NMR [J].