GROWTH SUPPRESSION OF MKN-28 HUMAN STOMACH-CANCER CELLS BY WASABI (EUTREMA-WASABI MAXIM)

被引:7
作者
FUKE, Y
OHISHI, Y
IWASHITA, K
ONO, H
SHINOHARA, K
机构
来源
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 1994年 / 41卷 / 10期
关键词
D O I
10.3136/nskkk1962.41.709
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The water extract fraction of wasabi (Eutrema wasabi Maxim.) markedly suppressed the growth of MKN-28 human stomach cancer cells. When MKN-28 cells were cultured with more than 40 mul/ml of the water extract of wasabi, they were underwent morphological alteration with frequent cell death. The substances that suppressed the growth of MKN-28 cells were existed in the fraction consisting of components with molecular weights under 5000. The growth-inhibiting effect on MKN-28 cells was unaffected by treatment at 90-degrees-C for 10 min. Shinigrin and isothiocyanates which are main components of wasabi had no growth-inhibiting effect.
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页码:709 / 711
页数:3
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