PREPARATION OF CHIRAL 1,2-ALKANEDIOLS WITH BAKER YEAST-MEDIATED OXIDATION

被引：10

作者：

KOMETANI, T ^{[1
]}

MORITA, Y ^{[1
]}

FURUI, H ^{[1
]}

YOSHII, H ^{[1
]}

MATSUNO, R ^{[1
]}

机构：

[1] KYOTO UNIV, FAC AGR, KYOTO 606, JAPAN

来源：

CHEMISTRY LETTERS | 1993年 / 12期

关键词：

D O I：

10.1246/cl.1993.2123

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(S)-1,2-Alkanediols, which were the opposite configuration to those produced by baker's yeast-mediated bioreduction of corresponding 1-hydroxy-2-alkanones, were prepared by baker's yeast-mediated oxidation. Treatment Of racemic 1,2-alkanediols with baker's yeast under the aerobic condition followed by removal of the corresponding 1-hydroxy-2-alkanones, which were produced by enantioselective oxidation of (R)-1,2-alkanediols, afforded (S)-1,2-alkanediols.

引用

页码：2123 / 2124

页数：2

共 9 条

[1] BAKERS-YEAST MEDIATED TRANSFORMATIONS IN ORGANIC-CHEMISTRY [J].

CSUK, R ;

GLANZER, BI .

CHEMICAL REVIEWS, 1991, 91 (01) :49-97

[2]

FUJISAWA T, 1986, YUKI GOSEI KAGAKU KY, V44, P519

[3]

KOMETANI T, IN PRESS J FERMENT B

[4]

Levene PA, 1928, J BIOL CHEM, V77, P555

[5]

Levene PA, 1927, J BIOL CHEM, V74, P343

[6]

LEVENE PA, 1943, ORG SYN COLLECTIVE, V2, P545

[7]

LEVENE PA, 1928, J BIOL CHEM, V79, P475

[8] STEREOSPECIFIC ASYMMETRIC REDUCTION OF FUNCTIONALIZED KETONES [J].

RIDLEY, DD ;

STRALOW, M .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1975, (10) :400-400

[9]

SERVI S, 1990, SYNTHESIS-STUTTGART, P1

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