COMPOSITION OF MOUSE BRAIN MYELIN DURING DEVELOPMENT

被引:99
作者
HORROCKS, LA
机构
[1] Laboratory of Neurochemistry, Cleveland Psychiatric Institute, Cleveland, Ohio
关键词
D O I
10.1111/j.1471-4159.1968.tb08945.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Myelin was isolated from the brains of mice at ages of 14, 24, 41, 44, 47, and 182 days and the contents of lipid phosphorus, cholesterol, lipid galactose, alkenyl groups, ethanolamine phosphoglycerides, choline phosphoglycerides, sphingomyelin, and serine and inositol phosphoglycerides were determined. Significant differences in the composition relative to total lipid phosphorus were found in the myelin. At 14 days of age, the myelin had lower relative amounts of cholesterol, galactolipids, alkenyl groups, and ethanolamine phosphoglycerides and a higher relative amount of choline phosphoglycerides. Copyright © 1968, Wiley Blackwell. All rights reserved
引用
收藏
页码:483 / &
相关论文
共 28 条
[1]  
ANSELL GB, 1966, VARIATION CHEMICA ED, P46
[2]   PREPARATION + SOME PROPERTIES OF PURIFIED MYELIN FROM CENTRAL NERVOUS SYSTEM [J].
AUTILIO, LA ;
TERRY, RD ;
NORTON, WT .
JOURNAL OF NEUROCHEMISTRY, 1964, 11 (01) :17-&
[3]   DESMOSTEROL IN RAT BRAIN MYELIN [J].
BANIK, NL ;
DAVISON, AN .
JOURNAL OF NEUROCHEMISTRY, 1967, 14 (05) :594-+
[4]  
BARTLETT GR, 1959, J BIOL CHEM, V234, P466
[5]  
BOWMAN RE, 1962, CLIN CHEM, V8, P302
[6]   METABOLISM OF 14C-LABELLED OLEIC ACID ERUCIC ACID AND NERVONIC ACID IN RATS [J].
CARROLL, KK .
LIPIDS, 1966, 1 (03) :171-+
[7]   PHOSPHOLIPID AND GLYCOLIPID PATTERNS OF INFANT AND FOETAL BRAIN [J].
CLAUSEN, J ;
LOU, HOC ;
ANDERSEN, H .
JOURNAL OF NEUROCHEMISTRY, 1965, 12 (07) :599-+
[8]   CHEMICAL COMPOSITION OF VERTEBRATE MYELIN AND MICROSOMES [J].
CUZNER, ML ;
DAVISON, AN ;
GREGSON, NA .
JOURNAL OF NEUROCHEMISTRY, 1965, 12 (06) :469-&
[9]   METABOLISM OF CELLULAR MEMBRANE SULPHOLIPIDS IN RAT BRAIN [J].
DAVISON, AN ;
GREGSON, NA .
BIOCHEMICAL JOURNAL, 1966, 98 (03) :915-&
[10]   MYELINOGENESIS IN RAT BRAIN [J].
DAVISON, AN ;
CUZNER, ML ;
BANIK, NL ;
OXBERRY, J .
NATURE, 1966, 212 (5068) :1373-&