学术探索
学术期刊
新闻热点
数据分析
智能评审

GLC DETERMINATION OF PSEUDOPHEDRINE AND RELATED EPHEDRINES IN SERUM AS HEPTAFLUOROBUTYRYL DERIVATIVES

被引：54
作者：
CUMMINS, LM
FOURIER, MJ
机构：
[1] Department of Chemical Pharmacology, Abbott Laboratories, North Chicago
来源：
ANALYTICAL LETTERS | 1969年 / 2卷 / 07期
关键词：
determination; electron capture detection; ephedrine; gas chromatography; heptafluorobutyryl derivatives; methylephedrine; norephedrine; pseudoephedrine; serum;
D O I：
10.1080/00032716908051314
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A method capable of determining therapeutic blood levels of pseudoephedrine in man is described. The procedure involves partial purification by extraction, formation of the heptafluorobutyryl derivative, and electron capture detection of the prepared derivatives. Serum levels of pseudoephedrine in man are presented. Chemical reactivity, stability and gas chromatographic properties of the ephedrine derivatives are discussed. Copyright © 1969 by Marcel Dekker, Inc.
引用
收藏
页码：403 / &
相关论文
共 3 条
1