EFFECT OF OMEGA-CONOTOXIN GVIA ON NEUROTRANSMITTER RELEASE AT THE MOUSE NEUROMUSCULAR-JUNCTION

被引：49

作者：

PROTTI, DA ^{[1
]}

SZCZUPAK, L ^{[1
]}

SCORNIK, FS ^{[1
]}

UCHITEL, OD ^{[1
]}

机构：

[1] UNIV BUENOS AIRES,FAC MED,INST BIOL CELULAR,BUENOS AIRES,ARGENTINA

来源：

BRAIN RESEARCH | 1991年 / 557卷 / 1-2期

关键词：

OMEGA-CONOTOXIN; NEUROTRANSMITTER RELEASE; NEUROMUSCULAR JUNCTION; VOLTAGE SENSITIVE CALCIUM CHANNEL; SPONTANEOUS QUANTAL RELEASE; K+-INDUCED QUANTAL RELEASE; ELECTRICALLY EVOKED RELEASE;

D O I：

10.1016/0006-8993(91)90156-P

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effect of omega-conotoxin GVIA (omega-CgTx) was studied on spontaneous, K+-induced and electrically evoked neurotransmitter release at the neuromuscular junction of mouse diaphragm. omega-CgTx decreased the frequency and amplitude of basal and K+-induced miniature end plate potentials. This effect was abolished by raising the extracellular Ca2+ concentration. omega-CgTx had no effect on the quantal content of the electrically evoked release in this preparation.

引用

页码：336 / 339

页数：4

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