PLATINOL (CDDP) AND CONTINUOUS INTRAVENOUS-INFUSION 5-FLUOROURACIL IN REFRACTORY STAGE-IV BREAST-CANCER - A PHASE-II STUDY

被引：13

作者：

BITRAN, JD ^{[1
]}

KOZLOFF, MF ^{[1
]}

DESSER, RK ^{[1
]}

机构：

[1] MICHAEL REESE HOSP & MED CTR,DEPT MED,HEMATOL ONCOL SECT,CHICAGO,IL 60616

来源：

CANCER INVESTIGATION | 1990年 / 8卷 / 3-4期

关键词：

D O I：

10.3109/07357909009012050

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twenty-four patients with refractory Stage IV breast cancer were teated with platinol (100 mg/m2 i.v. Day 1) and 5-fluorouracil (1000 mg/m2 as a continuous infusion over 24 h daily for 5 days). Objective responses occurred in 12 of 24patients (50% The median duration of response was 4.9 months. Platinol and 5-fluorouracil in combination are active agents in patients with refractory breast cancer, and clinical trials are warranted in previously untreated patients. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：335 / 338

页数：4

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