FC-GAMMA RECEPTOR HETEROGENEITY IN THE HUMAN PLACENTA

被引：28

作者：

KRISTOFFERSEN, EK ^{[1
]}

ULVESTAD, E ^{[1
]}

VEDELER, CA ^{[1
]}

MATRE, R ^{[1
]}

机构：

[1] UNIV BERGEN,GADE INST,DEPT MICROBIOL & IMMUNOL,N-5014 BERGEN,NORWAY

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1990年 / 32卷 / 05期

关键词：

D O I：

10.1111/j.1365-3083.1990.tb03197.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Fc receptors for IgG, FcRI (CD64), FcRII (OD32), and FcRIII (CD 16) in human placenta were studied by indirect immunohistochemistry using avidin biotin‐peroxidase complexes For the sunning of cryostat sections. The MoAb 32.2 against FcRI stained cells in the loose connective tissue of the placental villi. The MoAb IV3 (FcRII) and C1KM5 (FcRII) also stained stromal cells and in addition stained the endothelium of the placental villi. The MoAb anti‐Leu‐11b against FcRIII and BID6 against a 40‐kDa FcR from placenta stained both stromal cells and endothelium as well as the fetal trophoblasts lining the villi. The MoAb 3G8 (FcRIII) also stained trophoblasts and stromal cells but did not stain the endothelium The heterogeneity of FcR expression on human placenta is established. The function of the different receptors is still unclear. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：561 / 564

页数：4

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