MOLECULAR CHARACTERIZATION OF A PUTATIVE PEROXIDASE GENE OF DROSOPHILA-MELANOGASTER

被引：16

作者：

NG, SW ^{[1
]}

WIEDEMANN, M ^{[1
]}

KONTERMANN, R ^{[1
]}

PETERSEN, G ^{[1
]}

机构：

[1] UNIV HEIDELBERG, INST MOLEK GENET, NEUENHEIMER FELD 230, W-6900 HEIDELBERG, GERMANY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1171卷 / 02期

关键词：

PEROXIDASE GENE; (DROSOPHILA-MELANOGASTER);

D O I：

10.1016/0167-4781(92)90127-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified genomic clones and corresponding cDNAs that encode a putative peroxidase of Drosophila melanogaster. The gene (DmPO) appears as a single copy gene located on the third chromosome at position 89 D/E. It is interrupted by seven small introns and one unusually large 5' intron (about 11 kb). Sequence analysis of the cDNA showed an open reading frame of 690 amino acids resulting in a protein of 77 kDa. The deduced amino acid sequence reveals an overall homology to myelo-, eosinophil and thyroid peroxidase, a human superfamily of peroxidases.

引用

页码：224 / 228

页数：5

共 22 条

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