DIRECT ANALYSIS OF TUMOR-ASSOCIATED PEPTIDE ANTIGENS

被引：63

作者：

SLINGLUFF, CL

HUNT, DF

ENGELHARD, VH

机构：

[1] UNIV VIRGINIA, CTR CANC, CHARLOTTESVILLE, VA 22908 USA

[2] UNIV VIRGINIA, DEPT CHEM, CHARLOTTESVILLE, VA 22903 USA

[3] UNIV VIRGINIA, BEIRNE CARTER IMMUNOL CTR, DEPT MICROBIOL, CHARLOTTESVILLE, VA 22908 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 05期

关键词：

D O I：

10.1016/0952-7915(94)90077-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adoptive immunotherapy with tumor-specific cytotoxic T lymphocytes (CTLs) can induce tumor regressions in animals and in human cancer patients. Antigens recognized by CTLs from cancer patients are being sought as possible immunogens, a number of which have been identified during the past year. The ultimate result may be the development of novel peptide-based immunotherapies and a new understanding of the T-cell response to human cancer.

引用

页码：733 / 740

页数：8

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